It is eradicated predominantly by hepatic metabolism (largely CYP3A4) and is also transformed to an active metabolite with Homes similar to the mum or dad, sildenafil. The two sildenafil and the metabolite have terminal fifty percent life of about 4 hours.
It’s not acknowledged exactly what may possibly materialize if a female usually takes Viagra. At present, there are mixed opinions about the results in the drug in females.
i.d.) resulted in the sixty three% lessen of sildenafil AUC plus a fifty five% lessen in sildenafil Cmax . Concomitant administration of powerful CYP3A4 inducers, for example rifampin, is predicted to trigger better decreases in plasma levels of sildenafil.
You might have a headache soon after taking Viagra. Problems were being Just about the most common Unwanted effects in reports of the drug.
If you need help remembering to choose your dose of Viagra before intercourse, check out environment an alarm or downloading a reminder app. Or talk to your lover to remind you to definitely acquire your dose about an hour ahead of sex.
Get unexpected emergency professional medical assist When you've got indications of an allergic reaction to sildenafil: hives; problems breathing; swelling of your confront, lips, tongue, or throat.
Long lasting harm to the penis may well manifest if priapism isn't taken care of rapidly. Halt getting sildenafil and acquire emergency support Should you have any of the subsequent symptoms of priapism.
Lots of of such gatherings were reported click here to happen all through or Soon after sexual activity, and a few had been noted to take place Soon soon after using VIAGRA with out sexual action. Other individuals were noted to own occurred several hours to times after using VIAGRA and sexual activity. It is impossible to determine irrespective of whether these activities are connected straight to VIAGRA, to sexual action, for the affected person's underlying cardiovascular disease, to a combination of these factors, or to other aspects [see WARNINGS AND Safeguards and Affected person Details].
Kidney difficulties: If you have bad kidney functionality, you might need decreased doses of this medication. Kidney disease or minimized kidney purpose could bring about this medication to build up in the human body, resulting in Unwanted effects.
Viagra is not envisioned to damage an unborn newborn. Notify your health care provider If you're pregnant or system to become Expecting.
If you’re interested in figuring out more about OTC products that can be employed in place of Viagra, see this post.
VIAGRA doesn't guard you or your lover from finding sexually transmitted conditions, which include HIV—the virus that triggers AIDS.
In healthier male volunteers, there was no proof of a clinically major effect of azithromycin (five hundred mg every day for 3 days) around the systemic publicity of sildenafil or its main circulating metabolite.
In advance of using Viagra, tell your doctor about almost every other problems you've got or medications you're taking. They're able to recommend if Viagra is Safe and sound for you personally.